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Synthesis and antimicrobial activities of some new 1,2,4-triazole derivatives
1,3,4-Thiadiazole 1,2,4-triazole carbamate
2010/12/29
The synthesis of ethyl [3-(cyanomethyl)-5-alkyl-4H-1,2,4-triazol- 4-yl]carbamates (2a-d) was performed starting from ethyl 2-[ethoxy(4- (aryl)methylene]hydrazinecarboxylates (1a, 1b). The treatment of...
Synthesis and antimicrobial activities of some new biheterocyclic compounds containing 1,2,4-triazol-3-one and 1,3,4-thiadiazole moieties
1,2,4-triazol-3-one 5-thioxo-1,2,4-triazole
2010/10/18
2-(4-Amino-3-(4-chlorophenyl)-5-oxo-4,5--dihydro-1H-1,2,4-triazol- 1-yl)-N'-[(2,6-dihalogenophenyl)-methylene]acetohydrazides (3a,b) was obtained via the formation of 2-(4-amino-3-(4-chlorophenyl)-5-o...
Synthesis and antimicrobial activities of 2-(5-mercapto)-1,3-oxadiazol-2-ylmethyl-1,2,4-triazol-3-one derivatives
1,2,4-Triazole 1,3,4-oxadiazole Mannich base antimicrobial activity
2010/10/18
The synthesis of 4-amino-2-[(5-mercapto-1,3,4-oxadiazol-2- yl)methyl]-5-(4-methylphenyl)-2,4-dihydro-3H-1,2,4-triazol-3-one (2) and 4-amino-2-[(4-amino-5-mercapto-4H-1,2,4-triazol-3-yl)methyl]- 5-(4-m...
Synthesis of methyl (E)-2',4''-thiazachalcones and their N-alkyl derivatives, photochemistry with theoretical calculations and antimicrobial activities
Thiazachalcones N-decyl-4-thiazaclaconium bromide photodimerization antimicrobial activity
2010/4/8
A series of 9 new (E)-thiazachalcones (1-3), and their N-alkyl substituted derivatives (4-6), and stereoselective dimerization products (7-9) were synthesized, then tested for antimicrobial activity a...
Synthesis and Antimicrobial Activities of 1,2,4-Oxadiazin-5-one, 6-one and 5-Thiones
Amidoxime oxadiazine antimicrobial activity
2010/4/16
N-Substituted pyridine carboxamide oximes (2) were obtained from the reactions of pyridine hydroxamic acid chloride hydrochlorides (1) with primary amines. The reactions of carboxamide oximes with chl...
Synthesis and Antimicrobial Activities of Some New 1,2,4-Triazole Derivatives
Acyl hydrazone 1,2,4-triazole 1,3,4-oxadiazole Schiff Base reduction acetylation antimicrobial activity
2010/4/16
A series of acylhydrazones (2a-f) were synthesized by the condensation of iminoester hydrochlorides (1a-f) with acyl hydrazines. 2,5-Dialkyl 1,3,4-oxadiazoles (3a,c,e) were obtained in the same reacti...
Synthesis of Some Novel 3,5-Diaryl-1,2,4-Triazole Derivatives and Investigation of Their Antimicrobial Activities
Acyl hydrazone 1,2,4-triazole 1,3,4-oxadiazole Schiff base reduction acetylation antimicrobial activity antifungal activity
2010/4/16
A series of acylhydrazones (2a-d) was synthesized from the reactions of iminoester hydrochlorides (1a-e) with acyl hydrazines. 2,5-Dialkyl 1,3,4-oxadiazoles (3a-d) were obtained in the same reaction m...
Synthesis of Mannich Bases of Some 2,5-Disubstituted 4-Thiazolidinones and Evaluation of Their Antimicrobial Activities
2,5-Disubstituted 4-thiazolidinones synthesis Mannich bases antimicrobial activity
2010/4/20
4-Carbethoxymethyl-2-[(a -chloropropionyl/a -bromobutyryl/a-chloro-(a-phenyl)acetyl)amino]thiazoles (2a-c) were synthesized by the reaction of 4-carbethoxymethyl-2-aminothiazole (1) with a-chloropropi...
Synthesis and Antimicrobial Activities of Some New Flavonyl Pro-drug Esters of Ampicillin
Flavone derivatives Ampicillin Pro-drug ester Antimicrobial activities
2010/4/20
A new series of flavonyl pro-drug esters of ampicillin (Va-b) was prepared by condensing the appropriate bromomethyl flavone with ampicillin trihydrate potassium salt. Flavone derivatives and ampicill...