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Synthesis of Mannich Bases of Some 2,5-Disubstituted 4-Thiazolidinones and Evaluation of Their Antimicrobial Activities
2,5-Disubstituted 4-thiazolidinones synthesis Mannich bases antimicrobial activity
2010/4/20
4-Carbethoxymethyl-2-[(a -chloropropionyl/a -bromobutyryl/a-chloro-(a-phenyl)acetyl)amino]thiazoles (2a-c) were synthesized by the reaction of 4-carbethoxymethyl-2-aminothiazole (1) with a-chloropropi...