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Integrated analysis of variants and pathways in genome-wide association studies using polygenic models of disease
Integrated analysis of variants pathways genome-wide association studies polygenic models of disease
2012/9/18
Many common diseases are highly polygenic, modulated by a large number genetic factors with small effects on suscep-tibility to disease. These small effects are difficult to map reliably in genetic as...
Hierarchical Model Building, Fitting, and Checking: A Behind-the-Scenes Look at a Bayesian Analysis of Arsenic Exposure Pathways
Bayesian learning data management environmental health model validation
2009/9/24
In this article,we present a behind-the-scenes look at a Bayesian
hierarchical analysis of pathways of exposure to arsenic(a toxic heavy metal)
using the Phase I National Human Exposure Assessment ...
Product probability property, known in the literature as statistical
independence, is examined first. Then generalized entropies are introduced, all
of which give generalizations to Shannon entropy....