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喜报：海南大学计算机科学与技术学院2022级本科生周喆誉同学在TOP期刊Computers in Biology and Medicine发表论文（图）
周喆誉 Computers in Biology and Medicine 计算生物学
2024/7/1
近日，海南大学计算机科学与技术学院2022级本科生周喆誉同学在生物计算团队张子龙副教授的指导下，以第一作者在计算生物学期刊，题目为：“PSAC-6mA: 6mASite Identifier Using Self-Attention Capsule Network based on Sequence-Positioning”，论文网址链接为：https://www.sciencedirect.co...
近日，上海中医药大学中西医结合研究院国海东研究员和基础医学院吕嵘教授团队在三七皂苷R1（NGR1）靶向治疗心肌缺血损伤的作用及机制上取得重要进展，研究成果Notoginsenoside R1-loaded mesoporous silica nanoparticles targeting the site of injury through inflammatory cells improves ...
近日，复旦大学生物医学研究院许杰课题组分别在Oncogene和RSC Chemical Biology期刊发表研究论文，报道氨氯地平（amlodipine）对PD-L1的诱导自噬降解作用，以及PD1-PALM对PD-1的靶向降解作用。
天津大学药学院尉迟之光团队及国际合作团队在Nature Chemical Biology发文揭示双酰胺类药剂激活鱼尼丁受体的分子机理（图）
天津大学药学院 尉迟之光 双酰胺类药剂 鱼尼丁受体 分子机理
2020/8/25
2020年8月17日，天津大学尉迟之光团队和加拿大英属哥伦比亚大学Filip Van Petegem团队合作在Nature Chemical Biology发表了题为Structural basis for diamide modulation of ryanodine receptor的研究论文，首次阐明了双酰胺类药剂与鱼尼丁受体结合的结构基础，为进一步理解双酰胺的作用机理以及抗药性产生的机制提...
2019年6月6日,华南师范大学心理学院曲琛教授在PLOS Biology杂志（影响因子9.31）发表论文“Neurocomputational mechanisms at play when weighing concerns for extrinsic rewards, moral values, and social image”。该研究首次从神经计算层面揭示了大脑如何权衡外在奖励、道德价值...
浙江大学杜艺岭研究员在《Nature Chemical Biology》发表最新研究成果（图）
浙江大学 杜艺岭研究员 Nature Chemical Biology 天然产物分子 化合物
2017/6/28
天然产物分子及其衍生化合物长期以来是临床药物的重要来源。动植物和微生物等作为自然界的“合成化学家”，能够利用生物催化剂酶来催化合成那些目前通过有机化学反应不能合成、或者需要苛刻反应条件才能得到的具有复杂化学结构和重要生物学活性的分子。因此，对这些天然产物分子合成途径的挖掘及生物合成酶催化机制的解析，将为理性的生物合成途径设计与酶催化活性改造奠定基础。由此基础上采用现代合成生物学技术手段构建的天然产...
Agricultural practices, biology and quality of eggplant cultivated in Central Europe. A review
farming management fruit quality Solanum melongena L. temperate climate
2018/3/6
The eggplant is a warm-climate crop of high economic importance. In many Asian and Mediterranean countries, eggplants
are essential components of everyday dishes, while in Central Europe they have be...
2017药物化学和化学生物学研讨会（Symposia on Medicinal Chemistry and Chemical Biology）
2017 药物化学和化学生物学 研讨会
2017/1/13
Medicinal chemistry and chemical biology are stimulating fields that connect many scientific disciplines and allow for collaboration with other scientists in a wide variety of opportunities. The objec...
Shifting Attention From Theory to Practice in Philosophy of Biology
investigative practice gene concept evolutionary theory reductionism biology
2016/6/15
Traditional approaches in philosophy of biology focus attention on biological concepts, explanations, and theories, on evidential support and inter-theoretical relations. Newer approaches shift attent...
Varieties of Noise:Analogical Reasoning in Synthetic Biology
Synthetic biology interdisciplinarity analogical reasoning engineering sciences complex systems noise
2016/6/14
The picture of synthetic biology as a kind of engineering science has largely created the public understanding of this novel field, covering both its promises and risks. In this paper, we will argue t...
Diagrams as Locality Aids for Explanation and Model Construction in Cell Biology
cell biology diagram explanation locality aid model construction
2016/5/30
Using as case studies two early diagrams that represent mechanisms of the cell division cycle, we aim to extend prior philosophical analyses of the roles of diagrams in scientific reasoning, and speci...
Mathematical biology and the existence of biological laws
Laws Mathematical biology Contingency Dynamical systems Reducibility
2016/5/30
An influential position in the philosophy of biology claims that there are no biological laws, since any apparently biological generalization is either too accidental, fact-like or contingent to be na...
Complex emergence and the living organization:an epistemological framework for biology
autopoiesis biological autonomy complex emergence downward causation organization pattern generation
2016/5/27
In this article an epistemological framework is proposed in order to integrate the emergentist thought with systemic studies on biological autonomy, which are focused on the role of organization. Part...
Stark Spectroscopy:Applications in Chemistry,Biology and Materials Science
electroabsorption electrochromism electro-optic absorption electric field charge transfer
2016/5/23
Stark spectroscopy has been applied to a wide range of molecular systems and materials. A generally useful method for obtaining electronic and vibrational Stark spectra that does not require sophistic...
Professor Abruña, Héctor D，Department of Chemistry and Chemical Biology at Cornell University（图）
Professor Abruñ a, Héctor D Department of Chemistry and Chemical Biology at Cornell University
2015/11/4
Professor Usher, David A，Department of Chemistry and Chemical Biology at Cornell University,The Abruña Group focuses on the development and characterization of new materials using a wide variety...