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Modeling Spatial Correlation of DNA Deformation: DNA Allostery in Protein Binding
Modeling Spatial Correlation DNA Deformation DNA Allostery Protein Binding
2014/9/24
We report a study of DNA deformations using a coarsegrained mechanical model and quantitatively interpret the allosteric effects in protein−DNA binding affinity. A recent single-molecule study (...
Role of Protein Binding in Pharmacokinetics
pharmacokinetics；volume of distribution protein binding free drug concentration albumin
2018/4/10
This article describes the learning resources that are available to pharmacy students during a lecture on the role of protein binding in pharmacokinetics and pharmacodynamics as part of a clinical pha...