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南京农业大学农学院《Molecular Plant》发表万建民院士团队“The RNA binding protein EHD6 recruits the m6A reader YTH07 and sequesters OsCOL4mRNA into phase-separated ribonucleoprotein condensates to promote rice flowering”（图）
万建民 蛋白 相分离过程
2024/6/11
2024年5月9日，万建民院士团队与北京大学贾桂芳团队合作在Molecular Plant发表了题为The RNA binding protein EHD6 recruits the m6A reader YTH07 and sequesters OsCOL4mRNA into phase-separated ribonucleoprotein condensates to promote ric...
Demographic, lifestyle, and genetic determinants of circulating concentrations of 25-hydroxyvitamin D and vitamin D–binding protein in African American and European American women
African American European American racial disparity vitamin D vitamin D–binding protein
2018/11/14
Background: Vitamin D may have anticancer activities. The high prevalence of vitamin D deficiency in African Americans (AAs) may be a contributing factor to the cancer health disparities between AAs a...
Do Ligand Binding and Solvent Exclusion Alter the Electrostatic Character within the Oxyanion Hole of an Enzymatic Active Site
Pseudomonas putida Thiocyanates Anions Oxygen Steroid Isomerases Ligands Spectroscopy, Fourier Transform Infrared Kinetics Binding Sites Static Electricity
2016/5/24
The thousands of enzyme structures solved to date have consistently revealed that biological catalysis occurs within sequestered pockets containing complex interdigitations of polar and hydrophobic gr...
FTIR and Resonance Raman Studies of Nitric Oxide Binding to H93G Cavity Mutants of Myoglobin
Animals Nitric Oxide Imidazoles Myoglobin Enzyme Inhibitors Free Radical Scavengers Spectroscopy, Fourier Transform Infrared Spectrum Analysis, Raman Binding Sites Molecular Structure
2016/5/23
Nitric oxide (NO) binds to the myoglobin (Mb) cavity mutant, H93G, forming either a five- or six-coordinate Fe-NO complex. The H93G mutation eliminates the covalent attachment between the protein and ...
Systematic construction of tight-binding Hamiltonians for Topological Insulators and Superconductors
Systematic construction tight-binding Hamiltonians Topological Insulators Superconductors
2016/1/22
A remarkable discovery in recent years is that there exist various kinds of topological insulators and superconductors characterized by a periodic table according to the system symmetry and dimensiona...
An allosteric model of the inositol trisphosphate receptor with nonequilibrium binding
inositol trisphosphatereceptor adaptation overshoot nonequilibrium Monod- Wyman-Changeux model
2016/1/20
Theinositoltrisphosphatereceptor(IPR) is acrucialionchannelthat regulatestheCa 2+ influx from the endoplasmic reticulum (ER) to the cytoplasm. A thorough study of the IPR channel contributes to a bett...
Binding tactile and visual sensations via unique association by cross-anchoring between double-touching and self-occlusion
multimodal binding self-body observation double-touching self-occlusion cross-anchoring Hebbian learning
2015/7/30
Binding is one of the most fundamental cognitive functions, how to find the correspondence of sensations between different modalities such as vision and touch. Without a priori knowledge on this corre...
Stability of Mackerel (Trachurus japonicas) Hydrolysate with Iron-Binding Capacity in Simulated Gastrointestinal Fluids
Hydrolysate Iron-Binding Capacityc
2016/6/2
The aim of this study was to investigate the stability of mackerel (Trachurus japonicas) processing byproducts protein hydrolysate with iron-binding capacity in vitro simulated gastrointestinal system...
Optimal Portfolio Rules in Continuous Time When the Nonnegativity Constraint on Consumption is Binding
Optimal Portfolio Rules Continuous Time Consumption Binding
2015/5/13
Optimal Portfolio Rules in Continuous Time When the Nonnegativity Constraint on Consumption is Binding.
Enhanced Detection Strategies Accomplished Through Metal Binding and Miniature Mass Spectrometry
Metal binding Miniaturization Multiplexed MS/MS
2014/11/20
A multiplexed method for performing MS/MS on multiple ions simultaneously in a miniature rectilinear ion trap (RIT) mass spectrometer has been developed. This method uses an ion encoding procedure tha...
O2 Activation and Allosteric Zn(Ii) Binding on Hif-Prolyl Hydroxylase-2 (Phd2)
N-terminal transactivation domain pVHL von-Hippel Lindau protein
2014/11/20
Oxygen homeostasis is essential to the life of aerobes, which is regulated in humans by Hypoxia Inducible Factor-1α (HIF-1α). Under hypoxic conditions, HIF-1α transactivates over a hundred genes relat...
Optimization of Hydrolysis Conditions for Iron Binding Peptides Production from Shrimp Processing Byproducts
Iron Binding Peptides Production Hydrolysis
2016/6/2
Iron is one of the most popular trace elements in body and plays very important role in metabolism or construction of body. Organic iron from various sources for curing iron-deficiency anemia was one ...
Effect of Iron-fortified ‘Gari’, Cassava Meal on Serum Iron, Hemoglobin Concentration and Total Iron-binding Capacity in Albino Wistar Rats
Cassava Meal Serum Iron
2016/6/2
The effect of iron fortified ‘gari’, a cassava fermented meal on serum iron, hemoglobin concentration and total iron binding capacity on Albino Wistar rats were investigated. The prevalence of Iron De...
Modeling Spatial Correlation of DNA Deformation: DNA Allostery in Protein Binding
Modeling Spatial Correlation DNA Deformation DNA Allostery Protein Binding
2014/9/24
We report a study of DNA deformations using a coarsegrained mechanical model and quantitatively interpret the allosteric effects in protein−DNA binding affinity. A recent single-molecule study (...
Portfolio Selection with Small Transaction Costs and Binding Portfolio Constraints
portfolio constraints transaction costs long-run portfolio choice
2012/6/5
An investor with constant relative risk aversion and an infinite planning horizon trades a risky and a safe asset with constant investment opportunities, in the presence of small transaction costs and...