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Limitations of the review and meta-analysis of fish and PUFA intake and mild-to-severe cognitive impairment risks: a dose-response meta-analysis of 21 cohort studies
Limitation meta-analysis of fish 21 cohort studies
2018/12/13
The recent meta-analysis by Zhang et al. (1) on fish and PUFA intake and the risk of mild-to-severe cognitive impairment raises several methodologic issues that have important implications for the int...
Bioavailability of potassium from potatoes and potassium gluconate: a randomized dose response trial
adults bioavailability blood pressure controlled diet normotensive potassium
2018/12/3
Background: The bioavailability of potassium should be considered in setting requirements, but to our knowledge, the bioavailability from individual foods has not been determined. Potatoes provide 19–...
Consumption of fruit and vegetables and risk of frailty: a dose-response analysis of 3 prospective cohorts of community-dwelling older adults
fruits vegetables elderly frailty exhaustion slow walking speed
2018/12/3
Background: Consuming fruit and vegetables (FVs) may protect against frailty, but to our knowledge no study has yet assessed their prospective dose-response relation.
Consumption of dairy foods and diabetes incidence: a dose-response meta-analysis of observational studies
dairy milk yogurt cheese type 2 diabetes meta-analysis prospective/observational studies dose-response associations
2018/11/29
Background: A growing number of cohort studies suggest a potential role of dairy consumption in type 2 diabetes (T2D) prevention. The strength of this association and the amount of dairy needed is not...
Dietary vitamin D dose-response in healthy children 2 to 8 y of age: a 12-wk randomized controlled trial using fortified foods
dose response food fortification pediatric randomized controlled trial vitamin D
2018/11/23
Background: Vitamin D is fundamental for bone health. A high proportion of Canadian 2- to 8-y-olds do not meet the Estimated Average Requirement (EAR) of 400 IU/d.
Threshold estimation based on a p-value framework in dose-response and regression settings
estimation based p-value framework dose-response regression settings
2011/7/5
We use p-values to identify the threshold level at which a regression function takes off from its baseline value, a problem motivated by applications in toxicological and pharmacological dose-response...
Use of the Relative Dose Response (RDR) Assay to Determine Vitamin A Status of Calves at Birth and Four Weeks of Age
calves vitamin A relative dose response assay
2008/6/23
An accurate assessment of vitamin A status can be determined by analysis of liver biopsy samples; however, liver biopsies are not always feasible. Plasma concentrations of vitamin A do not provide an ...
Teaching Pharmacodynamics: An Introductory Module On Learning Dose-Response Relationships
Pharmacodynamics dose-response drug-receptor interaction Socratic teaching pharmacology
2018/3/26
The introductory pharmacodynamics course entitled, Principles of Pharmacology, was designed as an active-learning exercise to help students discover basic pharmacology principles associated with dose-...