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8月10日，Nature Genetics在线发表了夏来新与肖姗团队合作的题为“N6-Methyladenosine co-transcriptionally directs the demethylation of histone H3K9me2”的研究成果，研究首次发现m6A直接逆向调控抑制性组蛋白标记H3K9m2去甲基化的现象和机制，确立了RNA m6A修饰与组蛋白动态修饰之间的直接关系，揭...
Exploring the Status of Population Genetics:The Role of Ecology
California Tiger Salamander Ecology Ecological genetics Evolution Modern Synthesis Population biology Population genetics
2016/5/30
The status of population genetics has become hotly debated among biologists and philosophers of biology. Many seem to view population genetics as relatively unchanged since the Modern Synthesis and ha...
Discovery of Complex Regulatory Modules from Expression Genetics Data
Biostatistics Computational biology Expression genetics Genetics, Genomics
2014/12/18
Mapping of strongly inherited classical traits have been immensely helpful in understanding many important traits including diseases, yield and immunity. But some of these traits are too complex and a...
Causal graphical models in systems genetics: A unified framework for joint inference of causal network and genetic architecture for correlated phenotypes
Causal graphical models QTL mapping joint inference of phenotype network and genetic architecture systems genetics
2010/10/19
Causal inference approaches in systems genetics exploit quantitative trait loci (QTL) genotypes to infer causal relationships among phenotypes. The genetic architecture of each phenotype may be comple...
Bayesian Computation and Model Selection in Population Genetics
Bayesian Computation Model Selection Population Genetics
2010/3/17
Until recently, the use of Bayesian inference in population genetics was lim-
ited to a few cases because for many realistic population genetic models the
likelihood function cannot be calculated an...
Do indigenous Southern African cattle breeds have the right genetics for commercial production of quality meat?
Indigenous beef breeds Tenderness Yield Growth performance Pasture Feedlot
2012/8/13
The establishment of cattle breeds which are now indigenous to Africa is believed by historians to be very closely associated with man, his development, migration and specific behaviour from 6000 year...