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近日，上海中医药大学杨莉研究员团队受邀在质谱研究领域国际著名期刊Mass Spectrometry Reviews发表综述文章，题为Advances in mass spectrometry imaging for toxicological analysis and safety evaluation of pharmaceuticals。文章系统总结了基于“空间辨析、原位表征”理念的质谱成像分...
Richard N. Zare 来山东师范大学作“Mass Spectrometry, Drop by Drop”学术报告
Richard N. Zare 山东师范大学 学术报告 质谱分析法
2017/9/5
2017年8月29日上午，应科技处、化学化工与材料科学学院邀请，国际著名物理化学、分析化学家、美国科学院院士、中国科学院外籍院士、斯坦福大学Richard N. Zare教授，在千佛山校区作了题为“Mass Spectrometry, Drop by Drop”的学术报告。学术报告由校长唐波主持，化学院师生聆听了报告。 报告中，Richard N. Zare教授对质谱分析法的研究历史和现状做了深入...
Colocalization of the Ganglioside GM1 and Cholesterol Detected by Secondary Ion Mass Spectrometry
Cholesterol G(M1) Ganglioside Lipid Bilayers Spectrometry, Mass, Secondary Ion Molecular Conformation Biological Transport Microtechnology Nanotechnology Models, Molecular
2016/5/25
The characterization of the lateral organization of components in biological membranes and the evolution of this arrangement in response to external triggers remain a major challenge. The concept of l...
Supported Membrane Composition Analysis by Secondary Ion Mass Spectrometry with High Lateral Resolution
cryosolvents sugar glass glycerol water trytophan indole IR flourescence phosphorescence
2016/5/24
The lateral organization of lipid components within membranes is usually investigated with fluorescence microscopy, which, though highly sensitive, introduces bulky fluorophores that might alter the b...
Chemical cross-linking/mass spectrometry targeting acidic residues in proteins and protein complexes.
Chemical cross-linking/mass spectrometry targeting acidic residues proteins protein complexes.
2015/12/11
The study of proteins and protein complexes using chemical cross-linking followed by the MS identification of the cross-linked peptides has found increasingly widespread use in recent years. Thus far,...
Quantitative Analysis of Humectants in Tobacco Products Using Gas Chromatography (GC) with Simultaneous Mass Spectrometry (MSD) and Flame Ionization Detection
tobacco tobacco humectants Simultaneous Mass Spectrometry
2015/1/7
This paper describes the modification of an existing gas chromatographic (GC) method to incorporate simultaneous mass spectrometric (MSD) and flame ionization detection (FID) into the analysis of toba...
Enhanced Detection Strategies Accomplished Through Metal Binding and Miniature Mass Spectrometry
Metal binding Miniaturization Multiplexed MS/MS
2014/11/20
A multiplexed method for performing MS/MS on multiple ions simultaneously in a miniature rectilinear ion trap (RIT) mass spectrometer has been developed. This method uses an ion encoding procedure tha...
Development of Mass Spectrometry-Based Methods for Quantitation and Characterization of Protein Drugs: Transferrin as a Model Drug Delivery Vehicle
Mass Spectrometry O18 labeling Protein quantitation Transferrin
2014/11/20
In the last two decades, protein drugs have enjoyed a rapid growth and achieved a tremendous success in treating human diseases. However, the presence of physiological barriers greatly impedes the eff...
American Society for Mass Spectrometry
American Society for Mass Spectrometry American Society
2014/10/11
The American Society for Mass Spectrometry (ASMS) was formed in 1969 to promote and disseminate knowledge of mass spectrometry and allied topics. ASMS is a non-profit 501 c 3 corporation. Membership i...
Functional and Parametric Estimation in a Semi- and Nonparametric Model with Application to Mass-Spectrometry Data
Local linear regression Bandwidth selection Nonparamet-ric estimation
2013/6/13
Motivated by modeling and analysis of mass-spectrometry data, a semi- and nonparametric model is proposed that consists of a linear parametric component for individual location and scale and a nonpara...
Application of ultra-high performance liquid chromatography-mass spectrometry (UHPLC-MS) metabolomic fingerprinting to characterise GM and conventional maize varieties
chemometric analysis maize metabolomics
2014/2/24
The feasibility of metabolomic fingerprinting approach based on ultra-high performance liquid chromatography-quadrupole-time-of-flight mass spectrometry (UHPLC-QTOFMS) was studied to assess its abilit...
Application of Laser Ablation-Inductively Coupled Plasma-Mass Spectrometry to studies of chemical diffusion, sorption, and transport in natural rock
imbibition diffusion sorption transport rock
2017/4/11
We applied laser ablation-inductively coupled plasma-mass spectrometry (LA-ICP-MS) techniques to make spatial
measurements of chemical tracer concentrations in three natural rock types (tuff, sandsto...
Preparation of flaxseed for lignan determination by gas chromatography–mass spectrometry method
defatting extraction GC/MS hydrolysis lignans
2014/2/25
Since 1980s, several methods for the determination of lignans in food samples have been developed depending on the types of lignans and foods analysed, but mostly on flaxseed as a reference food. In t...
Liquid chromatography/mass spectrometry analysis of perfluoroalkyl carboxylic acids and perfluorooctanesulfonate in bivalve shells: Extraction method optimization
Perfluorinated carboxylic acids Perfluorooctanesulfonate Shell Soft tissue Acid digestion Solid phase extraction
2013/12/12
Different extraction methods, including extraction by organic solvents with and without acetic acid digestion,and mixed inorganic acid digestion coupled with solid phase extraction (SPE), were develop...
Synthesis, spectroscopic characterization, mass spectrometry, and crystal structure of N-{[(4-bromophenyl)amino]carbonothioyl}benzamide
Thiourea derivative X-ray structure determination mass fragmentation
2010/12/3
N-{[(4-bromophenyl)amino]carbonothioyl}benzamide was synthesized and characterized by IR, 1H- and 13C-NMR, mass spectrometry, and elemental analysis. The crystal structure was determined from single c...