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Electrochemical Investigation of Interactions between Potential DNA Targeted Compounds, 2,4-Di- and 2,3,4-Trisubstituted Benzimidazo[1,2-a]pyrimidines and Nucleic Acid
Electrochemical Investigation Interactions Potential DNA Targeted Compounds 2,4-Di- and 2,3,4-Trisubstituted Benzimidazo[1,2-a]pyrimidines Nucleic Acid
2010/9/17
The electrochemical aspects of interactions between DNA and two organic compounds are discussed herein. Potential DNA targeted compounds, 2-methyl-4-phenyl-benzo[4,5]imidazo[1,2-a]pyrimidine (C1) and ...
Supramolecular Self-Assembling Cyanine as an Alternative to Ethidium Bromide Displacement in DNA–Drug Model Interactions during High Throughput Screening
Supramolecular Self-Assembling Cyanine Ethidium Bromide Displacement DNA–Drug Model
2010/9/17
Supramolecular self-assembling cyanine and spermine binding to genomic DNA was a model for DNA–drug interactions during high throughput screening. Spermine competitively inhibited the self-assembly of...