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Transcription factor-pathway co-expression analysis reveals cooperation between SP1 and ESR1 on dysregulating cell cycle arrest in non-hyperdiploid multiple myeloma
coexpression cell cycle arrest multiple myeloma hyperdiploid
2016/1/25
Multiple myeloma is a hematological cancer of plasma B cells and remains incurable. Two major subtypes of myeloma, hyperdiploid MM (HMM) and non-hyperdiploid MM (NHMM), have distinct chromosomal alter...
Transcription factor-pathway co-expression analysis reveals cooperation between SP1 and ESR1 on dysregulating cell cycle arrest in non-hyperdiploid multiple myeloma
coexpression cell cycle arrest multiple myeloma hyperdiploid
2016/1/20
Multiple myeloma is a hematological cancer of plasma B cells and remains incurable. Two major subtypes of myeloma, hyperdiploid MM (HMM) and non-hyperdiploid MM (NHMM), have distinct chromosomal alter...
Assessing the public health relevance of a risk factor
Risk factor prevalence disease incidence relative risk population-attributable risk c-index
2013/4/27
In a recent series of high impact public health publications, the c-index was used as measure of prediction to assess the public health relevance of a risk factor. I demonstrate that the c-index is an...
A flexible observed factor model with separate dynamics for the factor volatilities and their correlation matrix
Correlated factors Inverse Wishart Markov chain Monte Carlo
2011/7/5
Our article considers a regression model with observed factors. The observed factors have a flexible stochastic volatility structure that has separate dynamics for the volatilities and the correlation...