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Explaining temporal trends in annualized relapse rates in placebo groups of randomized controlled trials in relapsing multiple sclerosis: systematic review and meta-regression
multiple sclerosis relapses annualized relapse rates placebo baseline characteristics eligibility criteria meta-analysis meta-regression systematic review
2013/4/27
Background: Recent studies have shown a decrease in annualised relapse rates (ARRs) in placebo groups of randomised controlled trials (RCTs) in relapsing multiple sclerosis (RMS).
Methods: We conduc...
Stochastic Search for Semiparametric Linear Regression Models
Stochastic Search Semiparametric Linear Regression Models
2011/7/6
This paper introduces and analyzes a stochastic search method for parameter estimation in linear regression models in the spirit of Beran and Millar (1987).
Local shrinkage rules, Lévy processes, and regularized regression
Local shrinkage rules Lévy processes regularized regression
2010/10/19
We use L\'evy processes to generate joint prior distributions for a location parameter $\bbeta = (\beta_1,...,\beta_p) $ as $p$ grows large. This leads to the class of local-global shrinkage rules. We...