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We construct optimal designs for estimating fetal malformation rate, prenatal death rate and an overall toxicity index in a toxicology study under a broad range of model assumptions. We use Weibull ...
A voting bloc is defined to be a group of voters who have similar voting preferences. The cleavage of the Irish electorate into voting blocs is of interest. Irish elections employ a “single transfer...
In randomized experiments, treatment and control groups should be roughly the same—balanced—in their distributions of pretreatment variables. But how nearly so? Can descriptive comparisons meaningf...
The problem of finding periodically expressed genes from time course microarray experiments is at the center of numerous efforts to identify the molecular components of biological clocks. We present...
A new class of Marginal Structural Models (MSMs), History- Restricted MSMs (HRMSMs), was recently introduced for longitudinal data for the purpose of defining causal parameters which may often be be...
Genome-wide association analysis has generated much discussion about how to preserve power 1 to detect signals despite the detrimental effect of multiple testing on power. We develop a weighted multi...

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