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Objective. To examine pharmacy students’ ownership of, use of, and preference for using a mobile device in a practice setting. Methods. Eighty-one pharmacy students were recruited and completed a pre...
The approach of exploiting highly conserved protein folds and structure in understanding protein function and in designing drugs leads to drugs that are less selective due to association with similar ...
探讨人单核细胞THP-1源性巨噬细胞产生的Lipocalin型前列腺素D合酶(lipocalin type prostaglandin D synthase,L-PGDS)、前列腺素E2(prostaglandin E2,PGE2)和前列腺素D2 (PGD2)与载脂蛋白A-Ⅰ (apolipoprotein A-Ⅰ,apoA-Ⅰ)抗动脉粥样硬化(atherosclerosis,AS)作用之间的关系...
研究鞘磷脂合酶2 (sphingomyelin synthase 2,SMS2)缺损对人结肠癌细胞(colon cancer cell,Caco-2)中药物转运体P糖蛋白(P-glycoprotein,P-gp)及多药耐药相关蛋白2 (multidrug resistance-associated protein 2,MRP2)的表达与功能的影响。方法 SMS2特异性siRNA转染至Caco-...
建立测定参茸珍宝片中特女贞苷含量的方法。方法 采用反相高效液相色谱法,色谱柱为Ultimate XB-C18-H (250 mm×4.6 mm,5 mm),流动相为甲醇-水(38∶62),流速为1.0 mL·min-1,检测波长为224 nm,进样量为10 μL。结果 特女贞苷进样量在0.053 44~1.603 3 mg内与峰面积积分值线性关系良好(r=0.999 9);平均加样回收率为96.9...
探讨临床分离鲍曼不动杆菌菌株生物膜形成能力及生物膜相关基因的分布情况, 分析其与细菌耐药表型的关系。方法 采用前瞻性研究方法, 收集山东省成武县人民医院 2012 年 10 月至 2013 年 10月分离的 70 株鲍曼不动杆菌, 采用 96 孔聚苯乙烯板构建生物膜模型, 结晶紫染色法定性、 定量分析生物膜形成能力, 比较不同生物膜形成能力鲍曼不动杆菌对亚胺培南、 阿米卡星、 美罗培南、 头孢吡肟...
Objective. To compare the impact of 2 different teaching and learning methods on student mastery of learning objectives in a pharmacotherapy module in the large classroom setting. Design. Two teachin...
测定46个不同产地种源草珊瑚叶、茎的生物量以及活性成分落新妇苷、迷迭香酸、异嗪皮啶含量,以总量为考查指标,筛选优良种源。方法 样品来自福建三明三元吉口采育场草珊瑚种植栽培示范区3年生成熟草珊瑚,每个产地随机取20株,分叶与茎,晾干,称量,计算成每10株叶、茎干品重量作为生物量;含量测定采用HPLC。色谱柱:Ultimate C18(250 mm×4.6 mm,5 μm);流动相A为乙腈-0.2%磷...
Objective. To describe the utility of concept mapping in a cardiovascular therapeutics course within a large classroom setting. Design. Students enrolled in a cardiovascular care therapeutics course ...
Objective. To evaluate the impact of counseling in a simulated medication adherence activity. Design. Students were randomized into 2 groups: patient medication monograph only (PMMO) and patient medi...
Objective. To evaluate the long-term effectiveness of an Australasian Society of Clinical Immunology and Allergy (ASCIA) anaphylaxis e-learning program compared to lectures or no training. Design. A ...
Objective. To design and implement 2 pharmaceutical industry elective courses and assess their impact on students’ selection of advanced pharmacy practice experiences (APPEs) and pursuit of pharmaceut...
Objectives. To evaluate whether a novel integrated longitudinal curricular activity to prepare graduating doctor of pharmacy (PharmD) students for 2 comprehensive examinations was successful, and to a...
建立高效液相色谱法测定氯雷他定含量及其5种有关物质。方法 采用Agilent TC-C18色谱柱(250 mm×4.6 mm,5 μm),以乙腈-2%冰醋酸溶液为流动相,梯度洗脱,流速为1.0 mL·min?1,检测波长为276 nm。结果 氯雷他定及其5种杂质分离良好。氯雷他定、地洛他定、N-甲基地洛他定、三环酮、杂质F、杂质I分别在3.2~106.7,0.97~ 58.3,0.59~35.5,...
Objective. To determine if the addition of weekly quizzes or reducing the number of faculty members teaching improved third-year (P3) pharmacy students’ final grades in a clinical pharmacokinetics cou...

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