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From GWAS to transcriptomics in prospective cancer design - new statistical challenges
Post -GWAS Transcriptomics Nested case -control Functional changes Biomarkers
2013/4/27
Background. With the increasing interest in post-GWAS research which represents a transition from genome-wide association discovery to analysis of functional mechanisms, attention has been lately focu...
A sparse regulatory network of copy-number driven expression reveals putative breast cancer oncogenes
sparse regulatory network copy-number driven expression reveals
2010/10/19
The influence of DNA cis-regulatory elements on a gene's expression has been intensively studied. However, little is known about expressions driven by trans-acting DNA hotspots. DNA hotspots harborin...